To date, only four studies examining the Chinese version of the MoCA 5-min protocol have been published (2 in Hong Kong and 2 in Nanjing) 4, 7, 12, 13. This protocol uses the same criteria (i.e., orientation, delayed recall and verbal fluency) from the full MoCA like the NINDS-CSN 5 min protocol, but with minor modifications in the assessment instruction and the grading system. 7, which was later named as the MoCA 5-min protocol 4. A second short version of MoCA was developed by Wong et al. When compared to other validated cognitive screening tasks, such as the full MoCA 10 as well as the Clinical Dementia Rating scale (CDR) 11, the diagnosis accuracy of NINDS-CSN 5-min protocol was found to be high with balanced sensitivity and specificity. suggested that the NINDS-CSN 5-min protocol could predict the occurrence of late onset MCI (i.e., 1-year after stroke), though its predictive validity was slightly poorer than the full MoCA 9. Another study which used the clinical diagnosis criteria of the American Heart Association/American Stroke Association for post-stroke dementia as the reference standard, found that the NINDS-CSN 5-min protocol has an acceptable discriminative power (sensitivity 82%, specificity 67%), and therefore can be a useful significant predictor of post-stroke dementia (odds ratio, 6.32) 8. are the first group to validate a short version of MoCA (i.e., NINDS-CSN 5-min protocol) in patients with stroke or transient ischemic attack (TIA), reporting that NINDS 5-min protocol was overall less effective to the full MoCA in screening MCI among patients with stroke or TIA 6. In accordance with the recommendations of the NINDS-CSN, two short versions of MoCA have been developed to date 6, 7. This assessment protocol is aimed to meet the requirement of busy clinics and also to allow for administration over the telephone, which is very promising and helpful for poststroke cognitive screening 5. In 2006, the National Institute for Neurological Disorders and Stroke-Canadian Stroke Networkproposed a 5-minute protocol that can be adopted as a possible cognitive screening tool for patients with stroke, by extracting three items (i.e., orientation, memory and verbal fluency) from the MoCA. In recent years, there has been an emerging interest in concentrating the most useful items from the MoCA into a similarly efficacious, but shorter version of MoCA. 15 min), with limited feasibility for use with patients with either low education levels, or with unstable conditions (e.g., frailty, severe attention deficits, and mind-wandering) 4. Although MoCA is primarily designed as a cognitive screening tool, it is still relatively time consuming (taking approx. Recent evidence has demonstrated that the MoCA is, at the present moment, the best screening tool for MCI (pooled sensitivity, 89% pooled specificity, 75%) 2, and that it is also an excellent screening tool for post-stroke cognitive impairment (pooled sensitivity, 81% pooled specificity, 79%) 3. in 1996, and was initially used and validated to detect mild cognitive impairment (MCI) and mild forms of Alzheimer’s disease 1. The Montreal Cognitive Assessment (MoCA) was developed by Nasreddine et al. The Chinese version of the MoCA 5-min protocol can be used as a valid screening for patients with stroke. These three assessments demonstrated equal performance in differentiating patients with stroke from controls. We found that the 5-min protocol did not differ from the MoCA in differentiating patients with cognitive impairments from those without (area under the receiver operating characteristic curve, AUC, of 0.948 for the MoCA 5-min protocol v.s. In this study, the Neurobehavioural Cognitive Status Examination (NCSE) was used as an external criterion of cognitive impairment. A total of 54 patients and 27 healthy controls were enrolled in this study. The aim of the present study was to examine the concurrent validity of 2 Chinese versions of the short version of the Montreal Cognitive Assessment (MoCA) in patients with stroke, i.e., MoCA 5-minute protocol and National Institute for Neurological Disorders and Stroke and Canadian Stroke Network (NINDS-CSN) 5-minute Protocol.
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